Medicinal Chemistry

Structure-activity relationships and rational drug design.

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Structure-Activity Relationships
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Drug Metabolism
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Study the chemical structure shown. Which functional group on the aromatic ring is chiefly responsible for this drug's activity and for its phase II conjugation?

Skeletal chemical structure diagram of paracetamol showing a benzene ring with a hydroxyl group and an acetamido side chain — Skeletal structure — identify the pharmacophore

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